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Khan W, Parveen R, Chester K, Parveen S, Ahmad S

Chronically high glucocorticoid levels induce neuronal atrophy and inhibit neurogenesis and synaptic plasticity in the hippocampus and prefrontal cortex, whereas excess IL-1 reduces BDNF production, collectively contributing to a depressed mood [306,307,308]

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IGF-1 levels return to baseline within 2 weeks of stopping tesamorelin

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